A compact, low-event home side meets a visitor whose away attack is much weaker than its home numbers suggest. The likely shape is a cautious game decided by one goal or a draw.
Lorient have kept six clean sheets in their last ten and won their last two home games 1-0 despite seeing little of the ball. Brest's high scoring is inflated by home games, including the 5-1 win on big expected goals. Away they have scored eight in ten, and their last two away games produced very little attacking threat.
Both midfields are thinner: Lorient are without two midfielders who also missed their goalless draw at Angers, and Brest are missing both first-choice centre-backs. That lowers tempo more than it adds goals. Lorient defend in a block and play for a single goal; Brest hold the ball but lack penetration.
That's why I'm leaning toward one side failing to score, with Lorient's clean-sheet record and Brest's weak away output as the reasons.