Lyon's midfield spacing sets the shape of this match. Its wide play through Athekame and Nakamura opens one route to the box, while Palace's central recoveries open another. Wharton and Timber have shown they can release Kamada and Pino quickly, with Larsen waiting ahead of them. The contest turns on which side gets its next pass to a clean receiver after the first press.
Lens found room behind Tolisso when he moved high, and Palace have the midfield pair to test that pocket. Timber's pass set up Kamada against Nottingham, while Larsen's shot created the rebound that Pino finished. Lyon's Athekame brings width and far-post runs, so Palace's back three will have to handle crosses as well as the next ball.
Openda is unavailable after playing against Lens, taking away Lyon's established runner behind the defence. Nakamura is expected to start, and Niakhaté has returned to training. Palace are without Mateta and cannot use Lerma in this competition, but Larsen, Kamada, Pino, Wharton and Timber all have recent match actions in the roles that drive this attack.
I expect the first midfield recovery to matter: Palace can move through Wharton or Timber into Kamada and Pino before Larsen attacks the box. Lyon can move the ball wide and bring Athekame forward, but its central finish now has a different shape. Palace's documented first pass and box receivers give them the clearest route to a winning finish, so I'm siding with Crystal Palace.