Dortmund's wingbacks can force Frankfurt's defenders to face their own goal and defend the next ball. Frankfurt can still escape directly through Burkardt and involve Doan or Ebnoutalib. The key is which side keeps making useful box contacts after the first attack is cleared. Valencia and Villarreal bring a sharper first-pass contest, with the home side's build-up meeting Villarreal's pressure and runs into the wide space.
Ryerson and Svensson can serve Guirassy or a far-side runner, while Dortmund's midfield can return cleared balls to the box. Frankfurt's recent shape changes have still allowed wide entries and rebounds. Karetsas and Prates missed Dortmund's last match and remain out, while Collins played Frankfurt's last game and is fit; the expected elevens remain projections. Dortmund's repeated supply is the stronger route through a tight period, so I'm siding with a Dortmund win.
Villarreal can press Valencia's first pass and use Comesaña to find Moleiro or another runner before the defence sets. Valencia have Danjuma and Gayà as outlets and can add home pressure, but their recent box entries have yielded few clean finishes. Villarreal made clear chances against Elche even with a rotated side, and Valencia's missing forward roles were already absent in recent games; Saliba's role remains uncertain. Villarreal's first pressure and surviving forward supply make me side with Villarreal to come away ahead.