Charlotte's compact counter can trouble Orlando, but Orlando have repeatedly found a first attacking receiver even when they surrender chances. The game turns on whether Charlotte can turn an opener into sustained separation. Columbus also have a strong first attack against D.C.'s changed lineup. Their next attack matters just as much, because D.C. retain ways to answer before the score stretches.
Charlotte can spring Toklomati and Biel from midfield, with Abada adding pace later. Orlando's Ojeda, Griezmann and Angulo have connected against several recent opponents, while Charlotte allowed substantial box volume to Portland and Philadelphia. Brekalo played Orlando's last game but is now suspended; Jansson and Dorsey missed it, and Atuesta is available again after suspension. Charlotte's Montreal score included an exceptional Abada finishing spell. Orlando's established attacking reception gives them a route to respond, so I'm siding with Orlando to stay close.
Columbus can use Tapia's runs and Chambost's delivery to test D.C.'s replacement goalkeeper and central cover. D.C. can still release Peglow or Ordaz and use Kurokawa's restarts for Bartlett; Kurokawa, Nono and Bartlett all completed the Toronto match. The current absences remove Munteanu, while Baribo is questionable after playing Cincinnati; Columbus's Méndez is available after missing two matches, with his role unsettled. Columbus have recently needed saves and efficient contacts despite allowing chances. D.C.'s remaining first and second contacts can bring a reply, so I'm siding with D.C. to stay close.